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Molecular Oncology Videos

In malignant tumors, pathways that control cell growth and cell death are disturbed.
In addition, the communication between tumor cells and their environment is altered.
For the successful treatment of a tumor by interfering with mechanisms governing
malignant growth, the molecular basis of these mechanisms should be understood
in detail. The videos on this website intend to serve this goal.
Once pathways can be targeted, new therapeutic options for cancer patients may ensue.

For a more in-depth understanding, the authors of the videos recommend
reading their books:

Video

Onkoview 2015

The EGF receptor tyrosine protein kinases

1 min read

Molecular Oncology Videos

Clonal evolution of tumours

The cell cycle – Part 2: Cyclins, cyclin dependent kinases (CDKs), CDK inhibitors

General aspects of signal transduction

The EGF receptor tyrosine protein kinases

The EGF receptor tyrosine protein kinases and the therapy of tumors with activated EGF receptors – Part 1: Inhibition of receptor activation via antibodies

The EGF receptor tyrosine protein kinases and the therapy of tumors with activated EGF receptors – Part 2: Blocking of EGF receptor signaling via tyrosine kinase inhibitors

BCR-ABL1 and the Philadelphia chromosome – Part 3: The BCR-ABL fusion protein

BCR-ABL1 and the Philadelphia chromosome – Part 1: Normal and aberrant karyograms

BCR-ABL1 and the Philadelphia chromosome – Part 2: The Philadelphia chromosome

BCR-ABL1 and the Philadelphia chromosome – Part 4: Therapy of tumors with BCR-ABL1 fusion proteins

Activation of mTORC1 in hamartoma syndromes and spontaneous tumors

TGF-beta signaling

Clonal evolution of tumours

The cell cycle – Part 2: Cyclins, cyclin dependent kinases (CDKs), CDK inhibitors

General aspects of signal transduction